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Trending Papers in epidemiology

DIY saline solution that's stronger than bleach to battle Covid
From Paper: Hypochlorous Acid: A Review
Michael S Block, Brian G Rowan
Published: Sep 2020
  • You can make a saline solution that is not caustic to humans and effective in killing COVID-19 on surfaces.
Diy saline solution (hypochlorous acid) and it's strong affects against Covid
From Paper: Fight Against COVID-19: ARCI’s Technologies for Disinfection
Published: Jun 2020
COVID-19 (SARS-CoV-2) is causing a huge concern to the global population due to its highly contagious properties. The SARS-CoV-2 is a new variant in the coronavirus family. The world is focussing on several methods to battle against this novel corona virus, including control of its spread. In this context, ARCI has quickly made efforts to develop disinfection systems including a UVC-based disinfection trolley, honeycomb air heater and a fogging chamber using UVC germicidal lamps, dry heat sterilization and HOCl-based chemical disinfectant to provide rapid and effective inactivation of microorganisms causing the pandemic. These systems have been successfully deployed at different hospitals for their validation.o
Pollen Explains Flu-Like and COVID-19 Seasonality
  • The results found a highly significant inverse association between pollen and changes in flu-like incidence corrected for incubation period.
  • Within this study, the authors combined changes in flu-like incidence per 100K/Dutch citizens with weekly pollen counts and meteorological data for the same period
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SARS-CoV-2 can survive for over 9 hours on human skin
From Paper: Survival of SARS-CoV-2 and influenza virus on the human skin: Importance of hand hygiene in COVID-19
  • The survival time was significantly longer for SARS-CoV-2 than for IAV [9.04 h (95% confidence interval: 7.96–10.2 h) vs. 1.82 h (1.65–2.00 h)]
  • The results show that SARS-CoV-2 may have a higher risk of contact transmission than IAV because it is much more stable on human skin. These findings support the hypothesis that proper hand hygiene is important for the prevention of the spread of SARS-CoV-2
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Acute ischemic stroke affects men and women differently
From Paper: Sex-specific lesion topographies explain outcomes after acute ischemic stroke
Bonkhoff, Anna K, et al
Published: Sep 2020
  • These findings have several important conceptual and clinical implications: 1) suggesting sex-specific functional cerebral asymmetries, and 2) motivating a sex-stratified approach to the management of acute ischemic stroke.
  • Female patients presented a more widespread pattern of stroke severity-relevant lesions than male patients. In addition, lesions in the posterior circulation of the left hemisphere underlay a higher stroke severity exclusively in women.
Dengue fever may provide some immunity to COVID-19
From Paper: How super-spreader cities, highways, hospital bed availability, and dengue fever influenced the COVID-19 epidemic in Brazil
Published: Sep 2020
  • The authors identified negative correlations between COVID-19's incidence, infection growth rate, and mortality to the percentage of people with antibody (IgM) levels for dengue fever in each of the country's states
  • The inverse correlation between COVID-19 and dengue fever was further observed in a sample of countries around Asia and Latin America, as well as in islands in the Pacific and Indian Oceans
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Low to moderate alcohol drinking is associated with better cognition in older age than complete abstinence from alcohol
From Paper: Association of Low to Moderate Alcohol Drinking With Cognitive Functions From Middle to Older Age Among US Adults
Published: Jun 2020
  • Weekly alcohol consumption had U-shaped relationships with the cognitive functions assessed, with the strongest associations with better cognitive functions at a dosage of 10 to 14 drinks per week for all participants
  • Low to moderate drinking was associated with consistently high cognitive function trajectories. Cognitive test scores at the baseline middle-aged assessment were relatively high and remained high at each subsequent assessment. In addition, there was a decreased rate of cognitive decline with age for middle-aged or older US adults for low to moderate drinkers
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People with low vitamin D levels are more likely to test positive for SARS-COV-2 infection
From Paper: SARS-CoV-2 positivity rates associated with circulating 25-hydroxyvitamin D levels
Published: Sep 2020
  • These results provide further rationale to explore the role of vitamin D supplementation in reducing the risk for SARS-CoV-2 infection and COVID-19 disease
  • The SARS-CoV-2 positivity rate was higher in the 39,190 patients with “deficient” 25(OH)D values (<20 ng/mL) (12.5%, 95% C.I. 12.2–12.8%) than in the 27,870 patients with “adequate” values (30–34 ng/mL) (8.1%, 95% C.I. 7.8–8.4%) and the 12,321 patients with values ≥55 ng/mL (5.9%, 95% C.I. 5.5–6.4%)
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Increased expression of TMPRSS2 in the upper respiratory tract may help explain why the incidence of COVID-19 among African-Americans is 2-3x the U.S. average
From Paper: Racial/Ethnic Variation in Nasal Gene Expression of Transmembrane Serine Protease 2 (TMPRSS2)
Published: Sep 2020
  • Given the essential role of TMPRSS2 in SARS-CoV-2 entry, higher nasal expression of TMPRSS2 may contribute to the higher burden of COVID-19 among Black individuals
  • TMPRSS2 expression was significantly higher in Black individuals compared with Asian, Latino, mixed race/ethnicity, and White individuals
Playing football for over 10 years in the NFL is associated with an increased mortality risk
From Paper: Mortality risk factors among National Football League players: An analysis using player career data
Published: Sep 2020
  • This paper finds evidence of both player health risk for increasing NFL seasons played and a survivorship bias among NFL players
  • The authors acknowledge a possible survivorship bias among players of Category I and II
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