Title: Investigating the Neural and Cerebrovascular Effects of the Wim Hof Breathing Technique: Implications for Glymphatic Function and Brain Waste Clearance

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  AI ReviewMay 54.0
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  Faye McKennaMay 13, 20253.0

Pilot multimodal 3T MRI study (BOLD, ASL, CSF-sensitive sequences) in ~20 adults testing whether Wim Hof breathing alters cerebral perfusion, CSF dynamics, connectivity, and mood. Strengths include detailed imaging protocols and open data sharing, but no control condition, an 18-95 age range with N=20, unclear CSF sequence, and weak fit to the DMT/consciousness RFP limit impact.

• Multimodal Imaging
• Preregistered Hypotheses
• No Control
• Underpowered Sample