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6
Reduced heart rate variability is associated with vulnerability to depression
Published: Sep 2020
  • The results suggest that reduced HRV is likely to be implicated in the risk of developing full-blown depression, rather than being a mere correlate of current depressive state
  • Self-reported psychological measures and three-minute resting-state ECG were collected in two at-risk populations [group with dysphoria (n = 27), group with past depression (n = 16)] and in a control group (n = 25)
Submitted by Patrick Joyce
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13
The experience of social rejection does not cause a person to act more friendly (or aggressive) in their next social interactions
From Paper: Does the Prospect of Fulfilling Belonging Affect Social Responses to Rejection? A Conceptual Replication Attempt:
Published: Jul 2018
  • After being socially rejected, do people behave friendlier (and less aggressive) to a person who is likely to socially accept them than those who do not? Contrary to the existing evidence, the current research found that socially rejected people do not change their responses.
  • The null results persisted after accounting for gender, attachment anxiety, attachment avoidance, fear of negative evaluation, rejection sensitivity, and self-esteem
Submitted by Naoyuki Sunami
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8
Stem cells administered via the nose can help treat schizophrenia
From Paper: Mesenchymal stem cells derived extracellular vesicles improve behavioral and biochemical deficits in a phencyclidine model of schizophrenia
Authors:
Tsivion-Visbord, Hadas, et al
Published: Sep 2020
  • MSCs-EVs treatment significantly restored a normal social pattern in these mice, as shown in a heat map representation of the time spent exploring the chambers and by quantitative measurement of that activity
  • The intranasal route for administration of drugs is especially advantageous for CNS access, convenient to use and can improve patient compliance. Another advantage of using MSCs-EVs is their ability to migrate to the site of injury, demonstrated in studies done by our research group and by others
Submitted by Will McBurnie
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4
Processes influencing heat transfer in the near-surface ice of Greenland’s ablation zone
Published: Oct 2018
  • A discrepancy between the measured ice temperatures and the mean air temperature implies some added heat from refreezing water in the upper 20 meters of ice in the ablation zone.
  • Near-surface ice temperatures measured through time in Western Greenland.
Submitted by Benjamin Hills
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3
A framework for attenuation method selection evaluated with ice-penetrating radar data at South Pole Lake
Published: May 2020
  • Framework tested for one dataset from an ice-penetrating radar survey at South Pole Lake.
  • Developed a framework for empirical methods used to measure attenuation in ice-penetrating radar.
Submitted by Benjamin Hills
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3
Measured Horizontal Temperature Gradients Constrain Heat Transfer Mechanisms in Greenland Ice
Published: Sep 2017
  • Strong horizontal temperature gradients indicate heat transfer by vertical advection and by latent heat transfer deep into the ice column.
  • Ice temperatures were measured in a 1km^3 block of ice in Western Greenland.
Submitted by Benjamin Hills
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16
82% of alcohol-related health studies were either authored or funded by alcohol companies
From Paper: Declared funding and authorship by alcohol industry actors in the scientific literature: a bibliometric study
Published: Sep 2020
  • This study investigates the extent and type of scientific research 1918–2019 which was supported by the alcohol industry, including alcohol companies themselves and other organizations, such as trade associations
  • The analysis included 13 481 unique records, 11 014 (82%) were authored or funded by alcohol companies and 2488 (18%) were authored or funded by other organizations
Submitted by Patrick Joyce
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3
Dengue fever may provide some immunity to COVID-19
From Paper: How super-spreader cities, highways, hospital bed availability, and dengue fever influenced the COVID-19 epidemic in Brazil
Published: Sep 2020
  • The inverse correlation between COVID-19 and dengue fever was further observed in a sample of countries around Asia and Latin America, as well as in islands in the Pacific and Indian Oceans
  • The authors identified negative correlations between COVID-19's incidence, infection growth rate, and mortality to the percentage of people with antibody (IgM) levels for dengue fever in each of the country's states
Submitted by Will McBurnie
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5
The development of an algorithm that can help optimize treatment for adolescent depression between pharmaceuticals and cognitive behavioral therapy
From Paper: Developing a data-driven algorithm for guiding selection between cognitive behavioral therapy, fluoxetine, and combination treatment for adolescent depression
Authors:
Meredith Gunlicks-Stoessel, Bonnie Klimes-Dougan, Adrienne VanZomeren, Sisi Ma
Published: Sep 2020
  • This model successfully stratified patients according to their responsiveness to a SSRI vs cognitive behavior therapy vs. a combination of the two
  • In this paper, machine-learning was applied to a wide range of demographic, clinical, and psychosocial data collected in treatment of adolescents with depression study (TADS) to build a model to predict overall treatment response after 12 weeks
Submitted by Patrick Joyce
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3
Using epigenetics to reconstruct the anatomy of an extinct species of humans
From Paper: Reconstructing Denisovan Anatomy Using DNA Methylation Maps
Authors:
Gokhman, David, et al
Published: Sep 2019
  • This system was tested by reconstructing the known anatomy of Neanderthal and chimp profiles based on their hypermethylated genes
  • The phenotype of methylation-based downregulation was inferred from known loss-of-function phenotypes
Submitted by Patrick Joyce
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