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A lack of neural plasticity in the hippocampus has been implicated in the development of depression. Ketamine is able to restore hippocampal plasticity in a rat model of depression, potentially illustrating a mechanism for the drug's anti-depressant effects

From Paper: Ketamine and its metabolite, (2R,6R)-HNK, restore hippocampal LTP and long-term spatial memory in the Wistar-Kyoto rat model of depression

Published:
Jun 2020
Submitted By:
Patrick Joyce
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