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Mutations in the vesicular trafficking protein annexin A1... | ResearchHub

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Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis

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Authors

Bradley Smith•Simon Topp•Christopher Shaw

Published

May 3, 2017

Abstract

Annexin A11 mutations, implicated in ALS, prevent binding to calcyclin and induce the formation of cytoplasmic inclusions.

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Journal

Science Translational Medicine

Topics

DOI

10.1126/scitranslmed.aad9157

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Support the authors with ResearchCoin

Journal

Science Translational Medicine

Topics

DOI

10.1126/scitranslmed.aad9157