8a:I[622484,["$4","$5","$6","$7","$8","$9","$a","$b","$c","$d","$e","$f","$10","$11","$12","$13","$14","$15","$16","$17","$18","$19","$1a","$1b","$1c","$1d","$20","$21","$22","$23","$24","$25","$26","$27","$28","$29","$2a","$2b","$2c","$2d","$2e","$2f","$30"],"WorkHeaderGrant"] 8b:Tf35,Immunology and Immune Disorders Objective This funding opportunity supports early-career researchers (BS, MS, PhD, MD, postdocs and faculty) pursuing innovative and exploratory projects in Immunology that are not readily supported by traditional funding mechanisms. Eligible projects should address fundamental or translational questions across immunology, including solid tumor immunotherapy, immune evasion, immune checkpoint biology, autoimmune disorder treatments, and innate immune sensing and pattern recognition, with a clear scientific rationale grounded in prior literature, existing data, or cross-disciplinary observations. Projects centered on reanalyzing and integrating existing public or private datasets will also be considered. The goal is to facilitate creative junior scientists to rapidly test high-risk, but feasible ideas that could advance our understanding of immune function, immune homeostasis, disease mechanisms or treatment. Priority will be given to projects that can generate meaningful proof of concept or preliminary insights within a 6 month timeframe, and that outline a clear path toward follow up funding, publication, or translational development. Rationale The immune system is a multifaceted, complex network integral for maintaining homeostasis. Cancerous cells, autoimmunity, and infections cause disruptions to this homeostasis, causing havoc in people’s daily lives. Despite considerable progress in understanding the mechanisms and interactions occurring in immune dysfunction, the full breadth of human immune interaction is incomplete. This results in a lack of functional treatments for solid tumors, autoimmunity, and rare infectious diseases. Progress in immune engineering, humanized animal models, and in-depth human datasets have made it possible to analyze the immune system in ways that were not feasible until recently. Junior and independent researchers are usually not able to obtain funding support to validate their creative, high-risk ideas. This forces them to pursue incremental advances in exchange for project funding and approval. By taking research risks into the unknown, we increase the probability of high-reward outcomes. This could lead to more transformative discoveries and should be encouraged and explored. Funding details $10,000 USD in ResearchCoin (RSC) is available to support this initial iteration, which may include data collection, laboratory analysis, reporting, and personnel costs. See ResearchHub’s funding guide for researchers to learn more about the process. Eligibility criteria Applicants must verify identity and authenticate ORCID on their ResearchHub profile There are no restrictions based on the applicant’s country of residence. PhD students, Postdocs, independent researchers, non-tenured faculty are eligible Projects should be feasible within the proposed 6 month timeframe using available infrastructure. Disclaimers and Open Science Commitment Preregistration: All selected applicants must preregister their study protocol on ResearchHub to be considered for funding. Fully funded pre-registrations will be eligible to be published as ResearchHub Registered Report (RRR) in the ResearchHub Journal (more info). Open-Access Data Sharing: By participating, applicants agree to share all data generated through this research in an open-access repository. This ensures transparency and facilitates the scientific community’s engagement with the findings. Preprint: Researchers are encouraged to upload a preprint of their findings on ResearchHub. Progress Updates: Researchers are encouraged to share regular updates via the “Updates” tab and may receive RSC tips for updates shared. Questions For questions, please post directly in the “Conversation” tab of the RFP or alternatively contact editorial@researchhub.foundation or Cole Delyea (cole.editor@researchhub.foundation).8c:Tf66,Immunology and Immune Disorders Objective This funding opportunity supports early-career researchers (BS, MS, PhD, MD, postdocs and faculty) pursuing innovative and exploratory projects in Immunology that are not readily supported by traditional funding mechanisms. Eligible projects should address fundamental or translational questions across immunology, including solid tumor immunotherapy, immune evasion, immune checkpoint biology, autoimmune disorder treatments, and innate immune sensing and pattern recognition, with a clear scientific rationale grounded in prior literature, existing data, or cross-disciplinary observations. Projects centered on reanalyzing and integrating existing public or private datasets will also be considered. The goal is to facilitate creative junior scientists to rapidly test high-risk, but feasible ideas that could advance our understanding of immune function, immune homeostasis, disease mechanisms or treatment. Priority will be given to projects that can generate meaningful proof of concept or preliminary insights within a 6 month timeframe, and that outline a clear path toward follow up funding, publication, or translational development. Rationale The immune system is a multifaceted, complex network integral for maintaining homeostasis. Cancerous cells, autoimmunity, and infections cause disruptions to this homeostasis, causing havoc in people’s daily lives. Despite considerable progress in understanding the mechanisms and interactions occurring in immune dysfunction, the full breadth of human immune interaction is incomplete. This results in a lack of functional treatments for solid tumors, autoimmunity, and rare infectious diseases. Progress in immune engineering, humanized animal models, and in-depth human datasets have made it possible to analyze the immune system in ways that were not feasible until recently. Junior and independent researchers are usually not able to obtain funding support to validate their creative, high-risk ideas. This forces them to pursue incremental advances in exchange for project funding and approval. By taking research risks into the unknown, we increase the probability of high-reward outcomes. This could lead to more transformative discoveries and should be encouraged and explored. Funding details $10,000 USD in ResearchCoin (RSC) is available to support this initial iteration, which may include data collection, laboratory analysis, reporting, and personnel costs. See ResearchHub’s funding guide for researchers to learn more about the process. Eligibility criteria Applicants must verify identity and authenticate ORCID on their ResearchHub profile There are no restrictions based on the applicant’s country of residence. PhD students, Postdocs, independent researchers, non-tenured faculty are eligible Projects should be feasible within the proposed 6 month timeframe using available infrastructure. Disclaimers and Open Science Commitment Preregistration: All selected applicants must preregister their study protocol on ResearchHub to be considered for funding. Fully funded pre-registrations will be eligible to be published as ResearchHub Registered Report (RRR) in the ResearchHub Journal (more info). Open-Access Data Sharing: By participating, applicants agree to share all data generated through this research in an open-access repository. This ensures transparency and facilitates the scientific community’s engagement with the findings. Preprint: Researchers are encouraged to upload a preprint of their findings on ResearchHub. Progress Updates: Researchers are encouraged to share regular updates via the “Updates” tab and may receive RSC tips for updates shared. Questions For questions, please post directly in the “Conversation” tab of the RFP or alternatively contact editorial@researchhub.foundation or Cole Delyea (cole.editor@researchhub.foundation). 8d:T3ae3,{"type":"doc","content":[{"type":"heading","attrs":{"id":"8a2e3c99-241e-4894-b48e-279adfecd95d","data-toc-id":"8a2e3c99-241e-4894-b48e-279adfecd95d","textAlign":"left","level":1},"content":[{"type":"text","text":"Immunology and Immune Disorders"}]},{"type":"heading","attrs":{"id":"e9066f95-118d-4f33-be72-48f7954caa0a","data-toc-id":"e9066f95-118d-4f33-be72-48f7954caa0a","textAlign":null,"level":1},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"16pt","fontFamily":"Arial, sans-serif","color":"rgb(103, 78, 167)"}},{"type":"bold"}],"text":"Objective"}]},{"type":"paragraph","attrs":{"id":"d26bb793-da89-48b0-8bcf-e4154732941b","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"This funding opportunity supports"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}},{"type":"bold"}],"text":" early-career researchers "},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"(BS, MS, PhD, MD, postdocs and faculty)"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}},{"type":"bold"}],"text":" "},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"pursuing innovative and exploratory projects in "},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}},{"type":"bold"}],"text":"Immunology "},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"that are not readily supported by traditional funding mechanisms. Eligible projects should address fundamental or translational questions across immunology, including "},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}},{"type":"bold"}],"text":"solid tumor immunotherapy, immune evasion, immune checkpoint biology, autoimmune disorder treatments, and innate immune sensing and pattern recognition"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":", with a clear scientific rationale grounded in prior literature, existing data, or cross-disciplinary observations. Projects centered on reanalyzing and integrating existing public or private datasets will also be considered."}]},{"type":"paragraph","attrs":{"id":"58845c5e-00c3-4148-98ff-dfe26e08a4a7","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"The goal is to facilitate creative junior scientists to "},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}},{"type":"bold"}],"text":"rapidly test high-risk, but feasible ideas"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":" that could advance our understanding of immune function, immune homeostasis, disease mechanisms or treatment. Priority will be given to projects that can "},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}},{"type":"bold"}],"text":"generate meaningful proof of concept or preliminary insights within a 6 month timeframe"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":", and that outline a clear path toward follow up funding, publication, or translational development. "}]},{"type":"heading","attrs":{"id":"a49a1546-1254-44fe-83aa-cbded8eaf7a8","data-toc-id":"a49a1546-1254-44fe-83aa-cbded8eaf7a8","textAlign":null,"level":1},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"16pt","fontFamily":"Arial, sans-serif","color":"rgb(103, 78, 167)"}},{"type":"bold"}],"text":"Rationale"}]},{"type":"paragraph","attrs":{"id":"9686f5c4-fb59-463b-afdd-80745d56e70c","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"The immune system is a multifaceted, complex network integral for maintaining homeostasis. Cancerous cells, autoimmunity, and infections cause disruptions to this homeostasis, causing havoc in people’s daily lives. Despite considerable progress in understanding the mechanisms and interactions occurring in immune dysfunction, the full breadth of human immune interaction is incomplete. This results in a lack of functional treatments for solid tumors, autoimmunity, and rare infectious diseases. Progress in immune engineering, humanized animal models, and in-depth human datasets have made it possible to analyze the immune system in ways that were not feasible until recently. "}]},{"type":"paragraph","attrs":{"id":"8a77b322-5453-42a0-a16c-a524e7b8ca11","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"Junior and independent researchers are usually not able to obtain funding support to validate their creative, high-risk ideas. This forces them to pursue incremental advances in exchange for project funding and approval. By taking research risks into the unknown, we increase the probability of high-reward outcomes. This could lead to more transformative discoveries and should be encouraged and explored."}]},{"type":"heading","attrs":{"id":"f6d78120-ac27-428e-8ec5-ac29266bd4bf","data-toc-id":"f6d78120-ac27-428e-8ec5-ac29266bd4bf","textAlign":null,"level":1},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"16pt","fontFamily":"Arial, sans-serif","color":"rgb(103, 78, 167)"}},{"type":"bold"}],"text":"Funding details"}]},{"type":"paragraph","attrs":{"id":"1767b56b-e1fc-4757-af18-bd29fb838fae","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}},{"type":"bold"}],"text":"$10,000 USD"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":" in ResearchCoin (RSC) is available to support this initial iteration, which may include data collection, laboratory analysis, reporting, and personnel costs. See ResearchHub’s"},{"type":"text","marks":[{"type":"link","attrs":{"href":"https://blog.researchhub.foundation/funding-for-researchers/","target":"_blank","rel":"noopener noreferrer nofollow","class":"link"}},{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":" "},{"type":"text","marks":[{"type":"link","attrs":{"href":"https://blog.researchhub.foundation/funding-for-researchers/","target":"_blank","rel":"noopener noreferrer nofollow","class":"link"}},{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(17, 85, 204)"}},{"type":"underline"}],"text":"funding guide for researchers"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":" to learn more about the process."}]},{"type":"heading","attrs":{"id":"e72cc64c-9043-41cd-9673-9cf9fa40dc6d","data-toc-id":"e72cc64c-9043-41cd-9673-9cf9fa40dc6d","textAlign":null,"level":1},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"16pt","fontFamily":"Arial, sans-serif","color":"rgb(103, 78, 167)"}},{"type":"bold"}],"text":"Eligibility criteria"}]},{"type":"bulletList","content":[{"type":"listItem","content":[{"type":"paragraph","attrs":{"id":"3f8a17d8-0625-45a5-ba12-75fecc9b643c","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"Applicants must verify identity and authenticate ORCID on their ResearchHub profile"}]}]},{"type":"listItem","content":[{"type":"paragraph","attrs":{"id":"46855807-1622-42ab-9a8c-e451e63cb3fb","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"There are no restrictions based on the applicant’s country of residence."}]}]},{"type":"listItem","content":[{"type":"paragraph","attrs":{"id":"78a6373d-21e2-4b3f-b05b-d5b4d81845e8","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"PhD students, Postdocs, independent researchers, non-tenured faculty are eligible"}]}]},{"type":"listItem","content":[{"type":"paragraph","attrs":{"id":"6b9338c2-a4ad-44fd-b9a8-0503978e6859","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"Projects should be feasible within the proposed 6 month timeframe using available infrastructure."}]}]}]},{"type":"heading","attrs":{"id":"19c70ed1-60dc-4637-bf50-3a2e0249c43b","data-toc-id":"19c70ed1-60dc-4637-bf50-3a2e0249c43b","textAlign":null,"level":1},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"16pt","fontFamily":"Arial, sans-serif","color":"rgb(103, 78, 167)"}},{"type":"bold"}],"text":"Disclaimers and Open Science Commitment"}]},{"type":"bulletList","content":[{"type":"listItem","content":[{"type":"paragraph","attrs":{"id":"c5c17421-1708-4016-a147-514737048d39","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"Preregistration: All selected applicants must preregister their study protocol on ResearchHub to be considered for funding."}]}]},{"type":"listItem","content":[{"type":"paragraph","attrs":{"id":"0e488cc3-87a1-46a9-b596-84ce7d7977dc","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"Fully funded pre-registrations will be eligible to be published as ResearchHub Registered Report (RRR) in the ResearchHub Journal ("},{"type":"text","marks":[{"type":"link","attrs":{"href":"https://docs.google.com/document/d/1QRNxCDh0KytkBcfP9P53LEIKurZpswKJyfB7eTX-J2I/edit?tab=t.0","target":"_blank","rel":"noopener noreferrer nofollow","class":"link"}},{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(17, 85, 204)"}},{"type":"underline"}],"text":"more info"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":")."}]}]},{"type":"listItem","content":[{"type":"paragraph","attrs":{"id":"b7d02078-3717-4dbb-b7ea-57a3fd32a0ae","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"Open-Access Data Sharing: By participating, applicants agree to share all data generated through this research in an open-access repository. This ensures transparency and facilitates the scientific community’s engagement with the findings."}]}]},{"type":"listItem","content":[{"type":"paragraph","attrs":{"id":"719a31e9-c4cc-45d3-816d-875799f55258","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"Preprint: Researchers are encouraged to upload a preprint of their findings on ResearchHub."}]}]},{"type":"listItem","content":[{"type":"paragraph","attrs":{"id":"a0c079de-9de3-4d7b-a7b1-7bf7e72af890","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"Progress Updates: Researchers are encouraged to share regular updates via the “Updates” tab and may receive RSC tips for updates shared."}]}]}]},{"type":"heading","attrs":{"id":"b514cbe0-91e7-4da8-9eac-60a1cd6b2fd5","data-toc-id":"b514cbe0-91e7-4da8-9eac-60a1cd6b2fd5","textAlign":null,"level":1},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"18pt","fontFamily":"Arial, sans-serif","color":"rgb(103, 78, 167)"}},{"type":"bold"}],"text":"Questions"}]},{"type":"paragraph","attrs":{"id":"a6e3a99e-8de8-4aba-b92f-8ab2e0791cad","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"For questions, please post directly in the “Conversation” tab of the RFP or alternatively contact "},{"type":"text","marks":[{"type":"link","attrs":{"href":"mailto:editorial@researchhub.foundation","target":"_blank","rel":"noopener noreferrer nofollow","class":"link"}},{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Roboto, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"editorial@researchhub.foundation"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Roboto, sans-serif","color":"rgb(0, 0, 0)"}}],"text":" or "},{"type":"text","marks":[{"type":"link","attrs":{"href":"https://www.researchhub.com/author/952195","target":"_blank","rel":"noopener noreferrer nofollow","class":"link"}},{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Roboto, sans-serif","color":"rgb(17, 85, 204)"}},{"type":"underline"}],"text":"Cole Delyea"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Roboto, sans-serif","color":"rgb(0, 0, 0)"}}],"text":" ("},{"type":"text","marks":[{"type":"link","attrs":{"href":"mailto:cole.editor@researchhub.foundation","target":"_blank","rel":"noopener noreferrer nofollow","class":"link"}},{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Roboto, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"cole.editor@researchhub.foundation"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Roboto, sans-serif","color":"rgb(0, 0, 0)"}}],"text":")"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"."}]},{"type":"paragraph","attrs":{"id":"b66e0bbd-70aa-46dc-a977-72c45db425fd","class":null,"textAlign":null}}]}8e:Tf66,Immunology and Immune Disorders Objective This funding opportunity supports early-career researchers (BS, MS, PhD, MD, postdocs and faculty) pursuing innovative and exploratory projects in Immunology that are not readily supported by traditional funding mechanisms. Eligible projects should address fundamental or translational questions across immunology, including solid tumor immunotherapy, immune evasion, immune checkpoint biology, autoimmune disorder treatments, and innate immune sensing and pattern recognition, with a clear scientific rationale grounded in prior literature, existing data, or cross-disciplinary observations. Projects centered on reanalyzing and integrating existing public or private datasets will also be considered. The goal is to facilitate creative junior scientists to rapidly test high-risk, but feasible ideas that could advance our understanding of immune function, immune homeostasis, disease mechanisms or treatment. Priority will be given to projects that can generate meaningful proof of concept or preliminary insights within a 6 month timeframe, and that outline a clear path toward follow up funding, publication, or translational development. Rationale The immune system is a multifaceted, complex network integral for maintaining homeostasis. Cancerous cells, autoimmunity, and infections cause disruptions to this homeostasis, causing havoc in people’s daily lives. Despite considerable progress in understanding the mechanisms and interactions occurring in immune dysfunction, the full breadth of human immune interaction is incomplete. This results in a lack of functional treatments for solid tumors, autoimmunity, and rare infectious diseases. Progress in immune engineering, humanized animal models, and in-depth human datasets have made it possible to analyze the immune system in ways that were not feasible until recently. Junior and independent researchers are usually not able to obtain funding support to validate their creative, high-risk ideas. This forces them to pursue incremental advances in exchange for project funding and approval. By taking research risks into the unknown, we increase the probability of high-reward outcomes. This could lead to more transformative discoveries and should be encouraged and explored. Funding details $10,000 USD in ResearchCoin (RSC) is available to support this initial iteration, which may include data collection, laboratory analysis, reporting, and personnel costs. See ResearchHub’s funding guide for researchers to learn more about the process. Eligibility criteria Applicants must verify identity and authenticate ORCID on their ResearchHub profile There are no restrictions based on the applicant’s country of residence. PhD students, Postdocs, independent researchers, non-tenured faculty are eligible Projects should be feasible within the proposed 6 month timeframe using available infrastructure. Disclaimers and Open Science Commitment Preregistration: All selected applicants must preregister their study protocol on ResearchHub to be considered for funding. Fully funded pre-registrations will be eligible to be published as ResearchHub Registered Report (RRR) in the ResearchHub Journal (more info). Open-Access Data Sharing: By participating, applicants agree to share all data generated through this research in an open-access repository. This ensures transparency and facilitates the scientific community’s engagement with the findings. Preprint: Researchers are encouraged to upload a preprint of their findings on ResearchHub. Progress Updates: Researchers are encouraged to share regular updates via the “Updates” tab and may receive RSC tips for updates shared. Questions For questions, please post directly in the “Conversation” tab of the RFP or alternatively contact editorial@researchhub.foundation or Cole Delyea (cole.editor@researchhub.foundation). 8f:T3ae3,{"type":"doc","content":[{"type":"heading","attrs":{"id":"8a2e3c99-241e-4894-b48e-279adfecd95d","data-toc-id":"8a2e3c99-241e-4894-b48e-279adfecd95d","textAlign":"left","level":1},"content":[{"type":"text","text":"Immunology and Immune Disorders"}]},{"type":"heading","attrs":{"id":"e9066f95-118d-4f33-be72-48f7954caa0a","data-toc-id":"e9066f95-118d-4f33-be72-48f7954caa0a","textAlign":null,"level":1},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"16pt","fontFamily":"Arial, sans-serif","color":"rgb(103, 78, 167)"}},{"type":"bold"}],"text":"Objective"}]},{"type":"paragraph","attrs":{"id":"d26bb793-da89-48b0-8bcf-e4154732941b","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"This funding opportunity supports"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}},{"type":"bold"}],"text":" early-career researchers "},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"(BS, MS, PhD, MD, postdocs and faculty)"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}},{"type":"bold"}],"text":" "},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"pursuing innovative and exploratory projects in "},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}},{"type":"bold"}],"text":"Immunology "},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"that are not readily supported by traditional funding mechanisms. Eligible projects should address fundamental or translational questions across immunology, including "},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}},{"type":"bold"}],"text":"solid tumor immunotherapy, immune evasion, immune checkpoint biology, autoimmune disorder treatments, and innate immune sensing and pattern recognition"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":", with a clear scientific rationale grounded in prior literature, existing data, or cross-disciplinary observations. Projects centered on reanalyzing and integrating existing public or private datasets will also be considered."}]},{"type":"paragraph","attrs":{"id":"58845c5e-00c3-4148-98ff-dfe26e08a4a7","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"The goal is to facilitate creative junior scientists to "},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}},{"type":"bold"}],"text":"rapidly test high-risk, but feasible ideas"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":" that could advance our understanding of immune function, immune homeostasis, disease mechanisms or treatment. Priority will be given to projects that can "},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}},{"type":"bold"}],"text":"generate meaningful proof of concept or preliminary insights within a 6 month timeframe"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":", and that outline a clear path toward follow up funding, publication, or translational development. "}]},{"type":"heading","attrs":{"id":"a49a1546-1254-44fe-83aa-cbded8eaf7a8","data-toc-id":"a49a1546-1254-44fe-83aa-cbded8eaf7a8","textAlign":null,"level":1},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"16pt","fontFamily":"Arial, sans-serif","color":"rgb(103, 78, 167)"}},{"type":"bold"}],"text":"Rationale"}]},{"type":"paragraph","attrs":{"id":"9686f5c4-fb59-463b-afdd-80745d56e70c","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"The immune system is a multifaceted, complex network integral for maintaining homeostasis. Cancerous cells, autoimmunity, and infections cause disruptions to this homeostasis, causing havoc in people’s daily lives. Despite considerable progress in understanding the mechanisms and interactions occurring in immune dysfunction, the full breadth of human immune interaction is incomplete. This results in a lack of functional treatments for solid tumors, autoimmunity, and rare infectious diseases. Progress in immune engineering, humanized animal models, and in-depth human datasets have made it possible to analyze the immune system in ways that were not feasible until recently. "}]},{"type":"paragraph","attrs":{"id":"8a77b322-5453-42a0-a16c-a524e7b8ca11","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"Junior and independent researchers are usually not able to obtain funding support to validate their creative, high-risk ideas. This forces them to pursue incremental advances in exchange for project funding and approval. By taking research risks into the unknown, we increase the probability of high-reward outcomes. This could lead to more transformative discoveries and should be encouraged and explored."}]},{"type":"heading","attrs":{"id":"f6d78120-ac27-428e-8ec5-ac29266bd4bf","data-toc-id":"f6d78120-ac27-428e-8ec5-ac29266bd4bf","textAlign":null,"level":1},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"16pt","fontFamily":"Arial, sans-serif","color":"rgb(103, 78, 167)"}},{"type":"bold"}],"text":"Funding details"}]},{"type":"paragraph","attrs":{"id":"1767b56b-e1fc-4757-af18-bd29fb838fae","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}},{"type":"bold"}],"text":"$10,000 USD"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":" in ResearchCoin (RSC) is available to support this initial iteration, which may include data collection, laboratory analysis, reporting, and personnel costs. See ResearchHub’s"},{"type":"text","marks":[{"type":"link","attrs":{"href":"https://blog.researchhub.foundation/funding-for-researchers/","target":"_blank","rel":"noopener noreferrer nofollow","class":"link"}},{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":" "},{"type":"text","marks":[{"type":"link","attrs":{"href":"https://blog.researchhub.foundation/funding-for-researchers/","target":"_blank","rel":"noopener noreferrer nofollow","class":"link"}},{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(17, 85, 204)"}},{"type":"underline"}],"text":"funding guide for researchers"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":" to learn more about the process."}]},{"type":"heading","attrs":{"id":"e72cc64c-9043-41cd-9673-9cf9fa40dc6d","data-toc-id":"e72cc64c-9043-41cd-9673-9cf9fa40dc6d","textAlign":null,"level":1},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"16pt","fontFamily":"Arial, sans-serif","color":"rgb(103, 78, 167)"}},{"type":"bold"}],"text":"Eligibility criteria"}]},{"type":"bulletList","content":[{"type":"listItem","content":[{"type":"paragraph","attrs":{"id":"3f8a17d8-0625-45a5-ba12-75fecc9b643c","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"Applicants must verify identity and authenticate ORCID on their ResearchHub profile"}]}]},{"type":"listItem","content":[{"type":"paragraph","attrs":{"id":"46855807-1622-42ab-9a8c-e451e63cb3fb","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"There are no restrictions based on the applicant’s country of residence."}]}]},{"type":"listItem","content":[{"type":"paragraph","attrs":{"id":"78a6373d-21e2-4b3f-b05b-d5b4d81845e8","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"PhD students, Postdocs, independent researchers, non-tenured faculty are eligible"}]}]},{"type":"listItem","content":[{"type":"paragraph","attrs":{"id":"6b9338c2-a4ad-44fd-b9a8-0503978e6859","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"Projects should be feasible within the proposed 6 month timeframe using available infrastructure."}]}]}]},{"type":"heading","attrs":{"id":"19c70ed1-60dc-4637-bf50-3a2e0249c43b","data-toc-id":"19c70ed1-60dc-4637-bf50-3a2e0249c43b","textAlign":null,"level":1},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"16pt","fontFamily":"Arial, sans-serif","color":"rgb(103, 78, 167)"}},{"type":"bold"}],"text":"Disclaimers and Open Science Commitment"}]},{"type":"bulletList","content":[{"type":"listItem","content":[{"type":"paragraph","attrs":{"id":"c5c17421-1708-4016-a147-514737048d39","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"Preregistration: All selected applicants must preregister their study protocol on ResearchHub to be considered for funding."}]}]},{"type":"listItem","content":[{"type":"paragraph","attrs":{"id":"0e488cc3-87a1-46a9-b596-84ce7d7977dc","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"Fully funded pre-registrations will be eligible to be published as ResearchHub Registered Report (RRR) in the ResearchHub Journal ("},{"type":"text","marks":[{"type":"link","attrs":{"href":"https://docs.google.com/document/d/1QRNxCDh0KytkBcfP9P53LEIKurZpswKJyfB7eTX-J2I/edit?tab=t.0","target":"_blank","rel":"noopener noreferrer nofollow","class":"link"}},{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(17, 85, 204)"}},{"type":"underline"}],"text":"more info"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":")."}]}]},{"type":"listItem","content":[{"type":"paragraph","attrs":{"id":"b7d02078-3717-4dbb-b7ea-57a3fd32a0ae","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"Open-Access Data Sharing: By participating, applicants agree to share all data generated through this research in an open-access repository. This ensures transparency and facilitates the scientific community’s engagement with the findings."}]}]},{"type":"listItem","content":[{"type":"paragraph","attrs":{"id":"719a31e9-c4cc-45d3-816d-875799f55258","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"Preprint: Researchers are encouraged to upload a preprint of their findings on ResearchHub."}]}]},{"type":"listItem","content":[{"type":"paragraph","attrs":{"id":"a0c079de-9de3-4d7b-a7b1-7bf7e72af890","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"Progress Updates: Researchers are encouraged to share regular updates via the “Updates” tab and may receive RSC tips for updates shared."}]}]}]},{"type":"heading","attrs":{"id":"b514cbe0-91e7-4da8-9eac-60a1cd6b2fd5","data-toc-id":"b514cbe0-91e7-4da8-9eac-60a1cd6b2fd5","textAlign":null,"level":1},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"18pt","fontFamily":"Arial, sans-serif","color":"rgb(103, 78, 167)"}},{"type":"bold"}],"text":"Questions"}]},{"type":"paragraph","attrs":{"id":"a6e3a99e-8de8-4aba-b92f-8ab2e0791cad","class":null,"textAlign":null},"content":[{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"For questions, please post directly in the “Conversation” tab of the RFP or alternatively contact "},{"type":"text","marks":[{"type":"link","attrs":{"href":"mailto:editorial@researchhub.foundation","target":"_blank","rel":"noopener noreferrer nofollow","class":"link"}},{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Roboto, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"editorial@researchhub.foundation"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Roboto, sans-serif","color":"rgb(0, 0, 0)"}}],"text":" or "},{"type":"text","marks":[{"type":"link","attrs":{"href":"https://www.researchhub.com/author/952195","target":"_blank","rel":"noopener noreferrer nofollow","class":"link"}},{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Roboto, sans-serif","color":"rgb(17, 85, 204)"}},{"type":"underline"}],"text":"Cole Delyea"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Roboto, sans-serif","color":"rgb(0, 0, 0)"}}],"text":" ("},{"type":"text","marks":[{"type":"link","attrs":{"href":"mailto:cole.editor@researchhub.foundation","target":"_blank","rel":"noopener noreferrer nofollow","class":"link"}},{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Roboto, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"cole.editor@researchhub.foundation"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Roboto, sans-serif","color":"rgb(0, 0, 0)"}}],"text":")"},{"type":"text","marks":[{"type":"textStyle","attrs":{"fontSize":"11pt","fontFamily":"Arial, sans-serif","color":"rgb(0, 0, 0)"}}],"text":"."}]},{"type":"paragraph","attrs":{"id":"b66e0bbd-70aa-46dc-a977-72c45db425fd","class":null,"textAlign":null}}]}90:T27fd,

Immunology and Immune Disorders

Objective

This funding opportunity supports early-career researchers (BS, MS, PhD, MD, postdocs and faculty) pursuing innovative and exploratory projects in Immunology that are not readily supported by traditional funding mechanisms. Eligible projects should address fundamental or translational questions across immunology, including solid tumor immunotherapy, immune evasion, immune checkpoint biology, autoimmune disorder treatments, and innate immune sensing and pattern recognition, with a clear scientific rationale grounded in prior literature, existing data, or cross-disciplinary observations. Projects centered on reanalyzing and integrating existing public or private datasets will also be considered.

The goal is to facilitate creative junior scientists to rapidly test high-risk, but feasible ideas that could advance our understanding of immune function, immune homeostasis, disease mechanisms or treatment. Priority will be given to projects that can generate meaningful proof of concept or preliminary insights within a 6 month timeframe, and that outline a clear path toward follow up funding, publication, or translational development.

Rationale

The immune system is a multifaceted, complex network integral for maintaining homeostasis. Cancerous cells, autoimmunity, and infections cause disruptions to this homeostasis, causing havoc in people’s daily lives. Despite considerable progress in understanding the mechanisms and interactions occurring in immune dysfunction, the full breadth of human immune interaction is incomplete. This results in a lack of functional treatments for solid tumors, autoimmunity, and rare infectious diseases. Progress in immune engineering, humanized animal models, and in-depth human datasets have made it possible to analyze the immune system in ways that were not feasible until recently.

Junior and independent researchers are usually not able to obtain funding support to validate their creative, high-risk ideas. This forces them to pursue incremental advances in exchange for project funding and approval. By taking research risks into the unknown, we increase the probability of high-reward outcomes. This could lead to more transformative discoveries and should be encouraged and explored.

Funding details

$10,000 USD in ResearchCoin (RSC) is available to support this initial iteration, which may include data collection, laboratory analysis, reporting, and personnel costs. See ResearchHub’s funding guide for researchers to learn more about the process.

Eligibility criteria

Applicants must verify identity and authenticate ORCID on their ResearchHub profile
There are no restrictions based on the applicant’s country of residence.
PhD students, Postdocs, independent researchers, non-tenured faculty are eligible
Projects should be feasible within the proposed 6 month timeframe using available infrastructure.

Disclaimers and Open Science Commitment

Preregistration: All selected applicants must preregister their study protocol on ResearchHub to be considered for funding.
Fully funded pre-registrations will be eligible to be published as ResearchHub Registered Report (RRR) in the ResearchHub Journal (more info).
Open-Access Data Sharing: By participating, applicants agree to share all data generated through this research in an open-access repository. This ensures transparency and facilitates the scientific community’s engagement with the findings.
Preprint: Researchers are encouraged to upload a preprint of their findings on ResearchHub.
Progress Updates: Researchers are encouraged to share regular updates via the “Updates” tab and may receive RSC tips for updates shared.

Questions

For questions, please post directly in the “Conversation” tab of the RFP or alternatively contact editorial@researchhub.foundation or Cole Delyea (cole.editor@researchhub.foundation).

91:T27fd,

Immunology and Immune Disorders

Objective

Rationale

Funding details

Eligibility criteria

Applicants must verify identity and authenticate ORCID on their ResearchHub profile
There are no restrictions based on the applicant’s country of residence.
PhD students, Postdocs, independent researchers, non-tenured faculty are eligible
Projects should be feasible within the proposed 6 month timeframe using available infrastructure.

Disclaimers and Open Science Commitment

Preregistration: All selected applicants must preregister their study protocol on ResearchHub to be considered for funding.
Fully funded pre-registrations will be eligible to be published as ResearchHub Registered Report (RRR) in the ResearchHub Journal (more info).
Open-Access Data Sharing: By participating, applicants agree to share all data generated through this research in an open-access repository. This ensures transparency and facilitates the scientific community’s engagement with the findings.
Preprint: Researchers are encouraged to upload a preprint of their findings on ResearchHub.
Progress Updates: Researchers are encouraged to share regular updates via the “Updates” tab and may receive RSC tips for updates shared.

Questions

For questions, please post directly in the “Conversation” tab of the RFP or alternatively contact editorial@researchhub.foundation or Cole Delyea (cole.editor@researchhub.foundation).

92:Tf64,Immunology and Immune Disorders Objective This funding opportunity supports early-career researchers (BS, MS, PhD, MD, postdocs and faculty) pursuing innovative and exploratory projects in Immunology that are not readily supported by traditional funding mechanisms. Eligible projects should address fundamental or translational questions across immunology, including solid tumor immunotherapy, immune evasion, immune checkpoint biology, autoimmune disorder treatments, and innate immune sensing and pattern recognition, with a clear scientific rationale grounded in prior literature, existing data, or cross-disciplinary observations. Projects centered on reanalyzing and integrating existing public or private datasets will also be considered. The goal is to facilitate creative junior scientists to rapidly test high-risk, but feasible ideas that could advance our understanding of immune function, immune homeostasis, disease mechanisms or treatment. Priority will be given to projects that can generate meaningful proof of concept or preliminary insights within a 6 month timeframe, and that outline a clear path toward follow up funding, publication, or translational development. Rationale The immune system is a multifaceted, complex network integral for maintaining homeostasis. Cancerous cells, autoimmunity, and infections cause disruptions to this homeostasis, causing havoc in people’s daily lives. Despite considerable progress in understanding the mechanisms and interactions occurring in immune dysfunction, the full breadth of human immune interaction is incomplete. This results in a lack of functional treatments for solid tumors, autoimmunity, and rare infectious diseases. Progress in immune engineering, humanized animal models, and in-depth human datasets have made it possible to analyze the immune system in ways that were not feasible until recently. Junior and independent researchers are usually not able to obtain funding support to validate their creative, high-risk ideas. This forces them to pursue incremental advances in exchange for project funding and approval. By taking research risks into the unknown, we increase the probability of high-reward outcomes. This could lead to more transformative discoveries and should be encouraged and explored. Funding details $10,000 USD in ResearchCoin (RSC) is available to support this initial iteration, which may include data collection, laboratory analysis, reporting, and personnel costs. See ResearchHub’s funding guide for researchers to learn more about the process. Eligibility criteria Applicants must verify identity and authenticate ORCID on their ResearchHub profile There are no restrictions based on the applicant’s country of residence. PhD students, Postdocs, independent researchers, non-tenured faculty are eligible Projects should be feasible within the proposed 6 month timeframe using available infrastructure. Disclaimers and Open Science Commitment Preregistration: All selected applicants must preregister their study protocol on ResearchHub to be considered for funding. Fully funded pre-registrations will be eligible to be published as ResearchHub Registered Report (RRR) in the ResearchHub Journal (more info). Open-Access Data Sharing: By participating, applicants agree to share all data generated through this research in an open-access repository. This ensures transparency and facilitates the scientific community’s engagement with the findings. Preprint: Researchers are encouraged to upload a preprint of their findings on ResearchHub. Progress Updates: Researchers are encouraged to share regular updates via the “Updates” tab and may receive RSC tips for updates shared. 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Drafts

Immunology and Immune Disorders

Drafts

Drafts

Immunology and Immune Disorders