The results revealed that quiescent satellite cells associated with myofibers could be activated by factors leaked from damaged myofibers that promote activation and proliferation in coordination with mitogens during muscle regeneration
To determine whether activated satellite cells are reversible to the quiescent-like state without cell division, individual muscle fibers were freshly isolated cultured with or without damaged myofibers for 48 hours
A comparative analysis between 'ephys' and calcium imaging data collected from a decision-making task in the frontal cortex show qualitative discrepancies at both the level of single cells and neural populations. Though, a new phenomenological model of the spike-to-fluorescence transformation helps explain many of the differences.
Electrophysiological recordings ('ephys') report spiking of neurons with high signal-to-noise ratio, temporal fidelity, and dynamic range, but typically offers access only to a sparse subset of relatively active neurons.
This work collects the little knowledge reached so far on the effects of NPS in male and female animal and human subjects, highlighting how much sex and gender differences in the effects of NPS has yet to be studied and understood
Men are more likely than women to use almost all types of illicit drugs and to present to emergency departments for serious or fatal intoxications
The results provide the first evidence for the role of oxytocin in threat-specific amygdala desensitization in humans and suggest that these effects are critically mediated by the serotonin system
No treatment main or interaction effects on amygdala threat reactivity were observed, yet oxytocin switched bilateral superficial amygdala sensitization to desensitization and this effect was significantly attenuated during decreased central serotonin signaling via pretreatment with ATD
The findings suggest that the practice of PA might improve aspects of executive function such as the ability to inhibit stimuli that trigger automatic responses, cognitive control ability, and mental flexibility in university students
binge drinking was associated with worse executive function in this same population, and this effect was stronger in women, which is exactly the reverse pattern of what we find with PA
Fitness of the surviving UV-induced MA lines was higher under daf-2 RNAi
This C. elegans study consisted of a mutation accumulation (MA) experiment with downregulated insulin signaling in half of the 400 MA lines by silencing daf-2 gene expression using RNA interference (RNAi) across 40 generations